Modafinil is considered a drug from the class of analeptics, the purpose of which is to stimulate the vital functions of our body. Scientists confirm an increase in concentration when taking modafinil, as well as improved memory and a surge of energy.

Although the mechanism of action of modafinil is not yet fully understood, it is believed that it modifies the concentration of neurotransmitters associated with sleep and awakening (for example, serotonin) and promotes a feeling of alertness.

Modafinil

In addition, some studies have suggested that taking modafinil increases dopamine levels, a neurotransmitter associated with both reward and addiction. Other studies have noted that people with food addictions are often found to be deficient in certain forms of dopamine. And since food can trigger dopamine release, the researchers speculated that uncontrolled eating might be an attempt to make up for this deficiency.

Modafinil – the benefits and effects of taking

The drug is used extensively in medicine for the treatment of hypersomnia and narcolepsy, but its properties do not end there.

  • Stimulates weight loss;
  • Reduces symptoms of bipolar disorder;
  • Treats depression, chronic fatigue, malnutrition and Parkinson’s disease;
  • Compensates for lack of sleep;
  • Fights high blood pressure.

How does modafinil work?

Scientists are still continuing to study the mechanism of action of modafinil on the human body. Today it is known that the drug affects various brain neurotransmitters that are responsible for intelligence, concentration and concentration. It is believed that it affects several different pathways in the brain and thus creates a stimulating effect and activates cognitive functions.

Modafinil activates the production of dopamine in the brain. Therefore, this drug is prescribed for people with hyperactivity (ADHD), whose dopamine levels are critically low, which causes problems with concentration and impaired attention.

How does modafinil work?

During clinical studies, modafinil was found to have neuroprotective and antioxidant properties. It helps to increase the level of cortical creatine and at the same time reduces oxidative processes in the brain, which also improves concentration. In addition, it inhibits the activity of compounds that are responsible for fatigue and, conversely, activates substances that promote wakefulness.

Modafinil is a drug from the class of analeptics (drugs intended to stimulate breathing and blood circulation). Once in the blood, modafinil crosses the blood-brain barrier (enters the brain) and lasts approximately 12 hours.

The effects of this drug are not fully understood, but some of them have been observed scientifically.

Modafinil raises histamine levels

Histamine is a mediator that is produced by the human body and plays an important role in many vital functions and the pathogenesis of various disease states. Its most famous role is participation in the body’s allergic reactions.

As a powerful nootropic, Modafinil helps improve memory, concentration, neural activity, and performance. Therefore, many take it as an energy drink. And this drug can actually be very helpful when it comes to performing tasks that require increased concentration, attention and staying awake for extended periods of time. In addition, modafinil improves mood and increases motivation.

Modafinil affects the brain by activating various biochemical processes in it. In particular, it stimulates the production of dopamine and related neurotransmitters, which indirectly increases the activity and improves the response (control functions) of the brain. These changes allow a person to solve mental problems more effectively, make quick decisions and maintain concentration for a long time.

Properties and mechanism of action

The mechanism of action of modafinil is different from that of amphetamine and ephedrine or other similar psychostimulants. Modafinil is also not formed in the human body from amphetamine or ephedrine derivatives.

Modafinil affects different parts of the brain. Probably the most important effect is the increased speed of mental reactions. This effect refers to the lower part of the diencephalon, the hypothalamus, where the activation of neural pathways occurs, in which the action of orexin / hypocretins is realized, which play an important role in the regulation of sleep-wakefulness as mediator substances.

Properties and mechanism of action

In addition, it activates the sympathetic alpha-1 receptors of the central nervous system, increases the activity of stimulation of glutamine and histamine transmitters, and also enhances the effects of serotonin in the cerebral cortex.

In addition, it reduces the activity of those inhibitory nerve cells in which gamma-aminobutyric acid acts as a transmitter. However, the exact mechanism by which modafinil promotes wakefulness is unknown.

Modafinil for weight loss

This drug has demonstrated effectiveness in obesity due to dopamine in the composition. As we all know, losing weight often becomes difficult because of a deficiency in certain forms of dopamine. We get it through fast carbohydrates, which contribute to weight gain, which is why evening binges and eating disorders also happen. Modafinil prevents this, as it fills the body with all the useful substances and helps to lose weight many times faster.

How to take according to the instructions

  • Daily dose – 200 mg in the morning or one hour before bedtime;
  • It is forbidden to take with cardiovascular diseases and liver pathologies.
How to take according to the instructions

Modafinil side effects

In a recent study, Oxford researchers reviewed all of the English-language literature published over 25 years on modafinil and concluded that the drug significantly improves concentration, goal-directedness, and learning (i.e., intelligence in its purest form) in healthy people without lack of sleep. Solving complex problems becomes easier. There are no side effects with this.

No matter how many useful properties can be attributed to modafinil, in any case, you can face dangers when using it.

  • An increased level of histamine, which means an opportunity to get skin peeling;
  • Indigestion due to the release of useful components in large quantities.